Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

This post may contain affiliate links. Please read my disclosure and privacy policy.

Scientific Spotlight: Journal Article Review on Metformin and PCOS

What you’ll learn in this episode

This episode explores the multifaceted role of Metformin in managing Polycystic Ovary Syndrome (PCOS). A medication known for its efficacy yet with a controversial reputation due to side effects, this episode aims to demystify Metformin, presenting both its potential benefits and the challenges it presents to women with PCOS.

The Science Behind Metformin and PCOS

Drawing from the recent research article, “Metformin: A New Approach” published in 2021, this episode aims to simplify the complex scientific discussions surrounding Metformin. You will learn more about the many benefits that metformin can offer PCOS as well as health in general. 

Real-World Experiences with Metformin

Hear firsthand accounts of how Metformin has influenced the PCOS journey for many, including my personal experience and client experiences. This real-world insight provides a balanced view of what potential users might expect, addressing common apprehensions and how to set yourself up to avoid and effectively manage any arising side effects. The practical tips in this episode will boost your comfort and effectiveness of Metformin treatment if it aligns with your health objectives.

Today’s topic is designed to demystify Metformin and help you gain new perspectives if it’s been recommended to you by your doctor for your PCOS management. Whether considering starting Metformin or optimizing its use, or to help you prepare for conversations with healthcare providers. Go ahead and listen now, because this episode is a great resource for making informed decisions that align with your health goals.

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Read The Full Episode Transcript Here

A really commonly talked about medication for PCOS is metformin. In today’s episode, I want to dive into the good, the bad, and the concerns that oftentimes arise for women with PCOS when thinking about taking metformin. So without further ado, let’s dive in.

You’re listening to the PCOS Repair Podcast, where we explore the ins and outs of PCOS and how to repair the imbalances in your hormones naturally with a little medical help sprinkled in. Hi, I’m Ashlene Korcek, and with many years of medical and personal experience with polycystic ovarian syndrome, it is my joy to watch women reverse their PCOS as they learn to nourish their body in a whole new way. With the power of our beliefs, our mindset, and our environment, and the understanding of our genetics, we can heal at the root cause.

Welcome back to the PCOS Repair podcast, where I’m excited to talk about a medication that is very helpful for PCOS, but gets a lot of bad reputation when it comes to women that have PCOS that are taking it. First of all, this is a research review episode, and so I want to start by going over the research. The whole research is going to be linked in the show notes below so that you can review any of it that you want yourself but for the purpose of the episode, I’m going to try to keep things really light and not overly scientifically worded, because I don’t particularly like reading journal articles. I find them fascinating, but I wish they would make the information a little bit more reader friendly. All right, so first of all, the article is called Metformin: A New approach and it was published in 2021. This is a fairly recent article, and it talks about the uses of metformin in general, and It also has a section that talks about it, specifically for PCOS at the end of the episode today, I will review the key takeaways and considerations. If you have taken it before, if you’ve been thinking about taking it, if you want to make an appointment and talk to a doctor about taking metformin for your PCOS, etc. The point of this episode is not to tell you to take metformin. It is simply to review some recent literature as well as to share some of my takeaways from having taken the medication as well as from clients that I’ve worked with that have taken the medication and what various women find and how best to combat any of the negative side effects.

Okay, so first of all, it has been found that metformin is very helpful in aiding in weight loss compared to the control groups in studies. The weight loss in the metformin group was significant. Side note on that, no medication is going to overcome food choices but if you’re doing everything right with your PCOS and you’re still struggling to lose weight or keep the weight off, or you feel like it’s such a struggle to lose weight, something like metformin can really help. The way that it helps is that it actually inhibits what we call the gluconeogenesis in the liver. This is where the liver is taking the stored glucose. You have blood sugar, you can send it to your cells and use it as energy right away, or you can store it. When we have excess glucose glucose, which we do pretty much every meal because we eat in chunks. We’re not just on a constant IV drip of glucose. We are eating, our body takes that and absorbs it from our intestines and then sends it to our bloodstream. Then our bloodstream signals insulin to then come and send it to where it needs to go in the body into our cells. So into our brain cells, into our muscle cells, wherever we need energy and nutrients. So that blood sugar goes in, it does the whole ATP thing that you may have heard about or you remember way back in high school chemistry. That’s where we get our energy but what if we have too much? We store it in two places. One, we store it in the liver and we have a set amount that sits in the liver and then once that store is full, then we send it to be stored as fat tissue. Then when we burn that fat tissue, we’re actually burning things a little bit different. It does not break down into glucose. It breaks down more into ketones and things like that but it’s a little bit different chemistry when we break fat but typically what we’re using on a daily basis is the food that you just consumed, and then we will break down in the liver. That’s a side note of physiology really simplified, but essentially that’s what the word gluconeogenesis is, is taking that storage out of the liver and bringing it back into the bloodstream.

Metformin inhibits that process. It’s going to start using what we have and stop storing it. Essentially, The way that not breaking down all this extra glucose from our liver allows for less blood sugar and then, of course, less insulin. We are just basically allowing our body to have breaks between meals. As long as you’re eating regular meals, this can be a really good thing because sometimes our body gets a little too excited to release more glucose before we needed it again. Metformin also slows down glucose absorption. This is going to decrease how sharp we spike our glucose as well then how much insulin is being fluttered into our system after we eat. If we are slowing down our absorption from our digestion, we can get a little bit and use it and a little bit and use it.

Then instead of having this massive flood of glucose all at once that spikes us super high and then it’s going to drop us, we can do it a little bit more gradually. Another way of thinking about this is what used to spike you really high because it was a super high sugar content is almost now acting like a food that’s maybe a little lower sugar content. Again, no medication is going to combat poor eating and poor nutrition. However, this gives us a little bit more leeway to be not quite so strict and still see results. In addition, metformin can indirectly increase our insulin sensitivity by increasing our peripheral glucose utilization. That’s all fancy jargon for basically saying the end point of our glucose use becomes more sensitive. Our muscles can take that glucose in better. Think about our insulin. If we go back to we ate something, our glucose spikes. Our metformin is helping to decrease that spike by absorbing it slower. Instead of being super high and then super crash, we have a rolling hill of blood sugar goes up. We’re slowly releasing, releasing, releasing, releasing over time, slowly, and then it starts to wane as we absorbed all of our meal and digested it.

Instead of this really sharp, just like, let it all in, let it all drop but once that blood sugar is in our system, once it has been released into our bloodstream, that glucose needs to go where it needs to end up, which is usually in our muscles and in our brain. One of the places where we can really improve our insulin sensitivity is our muscles but they have to accept that glucose. So This is where insulin comes in. Insulin is released. Our body recognizes the bloodstream has glucose in it. That blood glucose level tells our body, release the insulin but how much comes into how insulin sensitive we are. If we just need a little bit, it’s like a quiet, let the blood sugar in muscles, or do we need to shout, let the blood sugar in muscles? That’s the magnitude of how much insulin our body needs. If our body can just gently go, Hey, muscles, let the blood sugar in now, and our muscles just take that blood sugar in, we don’t need very much insulin. If we have to raise our insulin voice and scream at those muscles to let the blood sugar in, a lot more insulin needs to be released into our bloodstream.

When that happens, there’s a high concentration of insulin in our blood, and that high concentration of insulin tells our ovaries to produce more androgens. That’s where our reproductive hormones get messed up. That’s where our LH levels go up with the insulin effect, root cause of PCOS, which we talked about in a few episodes ago in a mini-series about the root causes. If you missed that, go back and listen to that but then there are some side effects, and these are the side effects that women talk about with PCOS. In fact, these side effects have been so notoriously talked about that the adherence rate to metformin has been very poor, and consequently, a lot of physicians have stopped prescribing it as heavily, especially with certain medications such as Ozempic on the market now for weight loss. Some physicians have gone more towards prescribing that. I probably should do a whole episode on that. I do not recommend that medication, I think metformin is a much better choice for root cause health of PCOS but that’s the whole side note. It’s my own opinion. I’ll do another episode on that one later. As far as the research, though, goes, there are some side effects.

The ones that are more concerning, and quite rare, are you can develop hypoglycemia with metformin. Now, as far as diabetic medications go, metformin is one of the lower-risk medications for developing hypoglycemia, but it can happen, as well as hyperinsulinemia and vitamin B deficiency and peripheral neuropathy, as well as acidosis but these were all fairly low compared to other diabetic medications. These are things that can happen. The ones that are very common, side effects, are lots of appetite, which is not highly It’s highly concerning as long as someone isn’t overly petite and would be in danger from having any a weight loss due to low appetite but it can cause some epigastric pain, so upper GI pain as well as some nausea and maybe some diarrhea. This GI discomfort, bloating, gas, nausea, diarrhea, just abdominal pain due to all of the digestive issues that can be going on. Then there’s studies that also suggest that metformin plays a role in our gut health and may promote healthy bacteria in our gut, which perhaps is how it helps to slow the digestion and so forth. That also may, my own theory aside, not in the research article here, may be why we have some GI upset at the beginning.

It’s not unlike when we start taking a pre or probiotic where we may have some bloating and some GI distress, and this is a pharmaceutical, so they’re usually a lot stronger than over-the-counter supplements. This is where, although some of these side effects can be annoying. We’ll talk about a little how to combat those and to help you determine if metformin may be something worth trying or retrying a slightly different approach. Basically, metformin has been shown to be an effective drug to reduce body weight in insulin sensitive and in insulin resistant patients, which is very exciting, but only in patients that are overweight. This isn’t something that usually creates weight loss in patients that are of healthy weight. This is where they actually have weight to lose. Also, I would put a caveat that they are probably actively following some weight loss plan, but this is making it more effective and they’re losing larger amounts over the course of the study compared to the control groups.

Then as far as PCOS and metformin, metformin has been shown in research to increase the ovulation rate in patients with PCOS as compared to the control or the placebo groups. However, it is not recommended as a first-line treatment for anovulatory cycles. Here’s the reason why something like Clomid or Letrozole is going to work so much better at focusing on the ovaries ovulating. The research is a little cloudy on whether or not it is helpful in combination. That would be like metformin and Clomid or metformin and Letrozole. That is a side research study that would probably need to be a lot larger and specifically looking at that. We don’t know if the metformin in combinations would increase the ovulation rates or not, but it’s not first-line as an ovulatory medication because clomid and letrozole are more effective. We’ll talk about more my take on PCOS and metformin as we review this article. This research article then also goes on to talk about metformin and its likelihood to either create a deficiency through lack of absorption or somehow creating deficient levels of vitamin B12. A lot of times, practitioners are monitoring for B12. Not a bad idea to take a B12 supplement if you are taking metformin but in addition to the benefits that we have already talked about, there are several cancers, and I’m not going to go into this because it’s not really the scope of this podcast, but I will list that metformin has been shown to improve breast cancer rates.

Of course, there are many different kinds of breast cancer, so not across the board, but there’s been shown to be improvement in survival rates in breast cancer, in lung cancer, in colorectal cancer. Essentially, there may be a lot of benefits to metformin beyond just the use in PCOS and diabetes as something that can create and sustain further metabolic health for people taking it. That concludes the research portion. Let’s dive into the takeaways here. First of all, I want you to think back to one of our episodes a few weeks ago that talked about all the different root causes and how connected they are. When we think about our cortisol, our insulin, and our inflammation, they are all connected. Metformin is primarily targeting the insulin system and decreasing our glucose effect as well as improving our insulin sensitivity. However, cortisol increases our insulin. Inflammation is made worse by high levels of cortisol and high levels of insulin and excess weight. Metformin does work on all of those, but it’s primarily doing it through the pathway of insulin. When we think about our root cause hormones, and then how they affect going up the pyramid towards our reproductive hormones and how they increase our androgens and throw off our cycle and create all of the side effects of PCOS and all of the problems that we see with PCOS, metformin definitely It definitely has its place in the treatment of PCOS.

The downsides are how well it’s tolerated. A couple of things that I want you to think about is if you have tried metformin, Perhaps you did this differently, and maybe that’s why it was not successful for you. You definitely want to start on a low dose. You want to slowly ease into it. You don’t want to go to a full dose right away. One reason, because you don’t want to be hypoglycemic, you don’t want to be too strong on yourself, which typically is less of a concern. So some doctors will go ahead and start you in a moderate to medium dose, and you could start a little less. So my recommendation would be to start at 500 milligrams. There’s a couple of different formulations out there, but basically 500 milligrams of metformin and I would take it in the evening with dinner. That seems to be the most tolerated. That way, you’re sleeping through some of the discomfort comfort, as well as starting with a lower dose and seeing how you tolerate it. As you tolerate it, increase it. What I personally have found and what I see repeatedly with women that tolerate it, now, I have seen women who do not tolerate it, but the ones who do end up tolerating it and having it be a non-factor as far as side effects, but very helpful as far as something that is assisting them with their goals for PCOS, is that when they start slow, they do have somewhere between three days to two weeks of discomfort.

Some women have had a little bit longer and they will push themselves a little bit longer but once that discomfort subsides, give yourself about that much time to settle in on that dose. If it took you five days to reach comfort, give yourself five days at comfort before you increase your dose to two five milligram tablets. Then from there, do the same thing till you reach the dose that your doctor wants you to be on but essentially, So you’re just starting in small increments, and then you’re giving yourself a couple of days to let your GI tract get used to it. Perhaps you take two weeks and then just steady for two weeks. There’s no race to get to that dosage. Again, we feel like I want this to work now. Well, if we overdo it, we start to go back and forth between, I’m on it, I’m not on it because I can’t tolerate it, and we want to find that sweet spot so that we can stay on it long term. If you have tried that and it did not work for you. It’s not the end all. It’s not the only drug out there, not the only option out there for your PCOS but I do want to bring it up because there’s been a lot of talk about how it’s not very friendly medication, how it has so many side effects but the couple of things I would really recommend is start extremely slow. If you felt like you could have started slower or you felt like you pushed yourself too fast, consider trying it again. The mindset piece here would be it may be for a couple of days and so take it easy on yourself, be patient with yourself, wear loose-fitting pants, don’t expect a whole lot else of yourself, take a hot bath in the evening, drink tea, don’t eat as much because the less you eat, the less they’ll be to bug your stomach, but eat enough that you’re comfortable. This also may be not the time and place to be your most healthy. It may be a time and place to be more carb-heavy. Sometimes a piece of toast digests better than eggs and bacon for breakfast or healthy omelet with lots of vegetables in it with your eggs. That’s okay because you’re trying to get yourself worked up on a medication that’s new to your system.

So be patient with yourself and do what’s needed. Typically, that doesn’t last for many days. It gets better and better as you go. For me, when I increase my dose, it takes me about three days. I don’t tend to be very sensitive to medications, and so I tend to handle things okay but if you are someone who tends to be sensitive, that doesn’t mean metformin is not going to happen for you, but definitely just start really slow. Start at the lowest dose you can. See how you do on it. As soon as you’ve had a couple of days where you’re doing well, increase it. Wait a couple more days till you level out again. Stabilize for a couple of days and then increase your dose until you reach that desired place. Also, make sure you’re taking a B12 supplement.

With that, I hope you found this article helpful. I will link the full article on the show notes on the website. It’s not when you scroll down, but when you go to the website, you’ll see all of the links in the show notes on the website. Until next time, if you have any questions, you can find me over on Instagram @nourishedtohealthy, and I look forward to talking to you there. Until our next episode. Bye for now.

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Episode #121: Zoe’s Self-Love to PCOS Health Victory

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This post may contain affiliate links. Please read my disclosure and privacy policy.

Zoe's Self-Love to PCOS Health Victory

What you’ll learn in this episode

I’m excited for you to listen to this episode where I share a real-life example of how impactful our self-talk can be to our PCOS health. I am honored to share a story of body acceptance, self-love, and the pursuit of balanced hormones through the experiences of Zoe, one of my clients who has successfully navigated the challenges of PCOS. Listen now as we explore how embracing where you currently are can catalyze profound changes in health and self-perception.

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Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

rate the podcast

Spread the Awareness

If you have found this podcast helpful please take just a moment to rate it and leave a review. This helps apple, spotify or whichever platform you use know to share this podcast with other women. I truely appreciate your help supporting as many women as possible ♥

Read The Full Episode Transcript Here

We’ve talked about self-love and embracing a positive body image a couple of times here on the PCOS Repair podcast but today, I’m really excited to share a story of one of the women I worked with and her journey to finding balanced hormones and better health and fitness by first accepting where she was currently at and putting a more practical spin on self-love and body acceptance and how we can use that to both become in an alignment with how we think about our bodies because we can’t be our bodies. We know what our thoughts are, we know how we feel about things. How can we create more alignment with that as well as using that to then give us a turbo boost to actually finally balancing those hormones and getting to where we want to be with our PCOS health. So with that, let’s dive in.

You’re listening to the PCOS Repair podcast, where we explore the ins and outs of PCOS and how to repair the imbalances in your hormones naturally with a little medical help sprinkled in. Hi, I’m Ashlene Korcek, and with many years of medical and personal experience with polycystic ovarian syndrome, it is my joy to watch women reverse their PCOS as they learn to nourish their body in a whole new way. With the power of our beliefs, Our mindset and our environment and the understanding of our genetics, we can heal at the root cause.

Welcome back to the PCOS Repair podcast, where today I’m really excited to share one of my client’s stories. Her name is Zoe, and she has very kindly allowed me to share her story here today. When we started working together, almost a year ago, I think, was about when we started working together, she was really frustrated. She’s early 20s, and she knows she’s had PCOS since she was maybe off by a year or two here, but she was end of high school, beginning of college. Okay, so around 18. She was diagnosed with PCOS due to irregular periods and facial hair and just at a normal regular exam. Her doctor had diagnosed her with that. She wasn’t having any specific health concerns at the time. She was able to manage things pretty well. She was an athlete in high school. As she was entering her early 20s, She was really struggling with breaking through certain plateaus. She had an image in her mind of how she wanted to look. She had an image of what body fat percentage would get her to that goal, as well as what size clothing she would be wearing and how she would look in pictures and in the mirror.

She had a very specific idea of what she wanted, and based on current advice, was doing her best to get there, but she kept hitting a plateau. If any of you have tried to change your body composition, by this, I mean changing your body fat percentage, not necessarily changing what the scale says. In fact, sometimes when we increase in muscle and we decrease in body fat, over time, we may end up actually weighing more than we did prior to setting out on this specific goal. For Zoe, she was trying to decrease her body fat percentage by about 5%, which is a fairly aggressive goal, especially since she was already what most people would consider a healthy weight but she wanted to have a very aggressively toned look. That’s neither here nor there. In fact, towards the end of this episode, we’ll talk about how this same concept applies, whether it’s your fertility or just your first couple of pounds that you want to lose, because this really isn’t about her specific goal. We’re going to tie this back into anybody’s specific goal and what they want to achieve in their PCOS health but she kept hitting a plateau of if she was trying to gain muscle, the amount of calories that she needed to consume to be able to work out at that level and to achieve that increase in muscle mass was her body was storing those extra calories as fat.

She was finding that very difficult to break through that ability. When we started working together, I could have given her more of the same advice of, Well, you need to do these exercises and you need to eat these foods but she honestly had her workouts pretty well dialed in, and her nutrition was pretty well dialed in, except that her calories were constantly going into a cycle of stressing out her body or overindulging the way her body was reading it. Now, anyone else would have looked at it and been like, Well, those are reasonable calories for someone who’s trying to gain muscle mass. The problem is that when our hormones are essentially in a mode where it’s more like you have to give a new agenda to to your body. When we tell our body, Hey, I want you to survive, then that’s where our body starts out. It’s just like, I’m going to keep you alive no matter what you do to me. I’m going to do my best to keep you alive as long as possible. If you restrict my calories, I’m going to I’m doing my best to maintain your living status until more food is available but what we have to somehow communicate to our bodies is that while we may be eating a little bit less, we have plenty, we don’t need to be scared. For long periods of time, when we’re restricting calories, what we essentially teach ourselves, and then add to that the PCOS genetics. So anybody is going to discover that if they go long periods of years of basically restricting calories extremely, and then periods of not restricting, and then going into another calorie deficit that’s very extreme. A small calorie deficit typically won’t have the same effect but when we’re talking these extreme diets where people are going down close to 1,000 calories a day or less, a lot of them are even less. There’s a couple situations which you are biohacking your body that it thinks it’s fasting that are a little bit different. If you have tapped into fat burning mode, you may be bypassing this. There can be a hack there. I’m not going to say blanket statement across the board but from the average person who is just on their own without assistance from somebody who really knows what they’re doing, if you’re restricting your calories to that degree, I would say anything below, I would say, 1,700 calories a day on average, but probably you could get away with 15 but again, it depends so much on your body size, on so many different things because 1,500 calories a day for some people is extremely low. Other women, that’s probably okay but again, there’s all sorts of calorie math that I run through with my clients and women inside my programs because it’s very specific to your height, your weight, your current calorie expenditure, and how much we want to decrease for current goals, and how much you’ve done in the past also plays a role into that.

Back to what we’re talking about. Basically, she had been doing this for so long that I didn’t like having her just continue as is and because she had been hitting these plateaus routinely of she would restrict calories to the point where she was burning muscle, but then at the same time, as soon as she started to eat a little bit more, her body would store this fat. The reason her body was doing that is because her body’s written instructions essentially were that if we finally get some food, we better store it. Basically, her insulin was telling her body to do that. Then because she was stressing her body, because she was in her early 20s and trying to climb the corporate ladder, there was plenty of stress in her life.

So her cortisol was also telling her body to store. Then just the fact her PCOS genetics, she had a tendency towards insulin resistance, even though her labs didn’t show that yet. Her insulin effect was affecting her ability to burn fat effectively the way that your average nutritionalist would think that this would work. When you’re working with someone who doesn’t understand the PCOS root causes, their mathematical equations of what your body is going to be able to do are very different, and they’re not reading the cues from your body of why this isn’t working. When you’re constantly you’re hitting the same plateaus or you feel like you’re hitting the same walls or hurdles, beat bumps, however you think of it in your mind, whenever you hit those over and over and over, you have to question why. So that’s where Zoe and I started this question, Why are we hitting these plateaus? And as I listened to her and the way she talked about things, even more than the way she was eating or the way she was exercising, what I heard was she felt like her body was letting her down. She felt like everything she’d been told should work It wasn’t working, and so she needed to push harder.

So we took several weeks to get to this point where finally I got her to agree, Hey, look, what’s the worst that could happen over a couple of months of doing it the way I’m thinking we should do it? And what if we, instead of pushing harder towards this goal that you have, what if we backed up and repaired some of what’s working against us? And you may gain some weight, actually. And she did. She actually gained, I think it was like 10 pounds, and she was very unhappy about this. And so what we had to work with this is how do we work with our body from a place of loving it and caring about it to provide it with what it needs rather than forcing it into an image that we have for how we want to be. One of the things that her and I worked with, and I want to share with you today, is that this is a mindset shift that is very, very, very difficult for us. Because we have in popular culture a lot of verbiage and imagery and focus and push towards we need to accept all body types.

We need to accept our body for what it is, and we need to love ourselves and all of this. But the problem is, is that where does that come in to where we have a goal for ourselves? There is a difference between accepting and almost like in a downward, I accept it is what it is what it is and it’s never going to get me better. That’s almost a negative. That’s not creating a positive body outlook, in my opinion. Where I like to take it is, how can we accept our body where it’s currently at? See it with empathy. See it with all of the things that it’s doing well. Appreciate it for all of the things that it’s doing well. Can we stand? Can we walk? Can we see? All of those wonderful things that our body is doing for us and instead of expecting the impossible from our body, what if we start working with our body to see where it can even grow further? So if we have a goal for ourselves, instead of pushing harder, instead of being more and more frustrated and angry with our bodies, Zoe’s journey was really a testament to how much it requires us to become in alignment with our bodies, to grow in our appreciation and our self-love from our bodies, and to ultimately take the steps that our body needs us to take next rather than rush straight to the finish line that we want.

So ultimately, what happened with Zoe? Like I said, she actually gained a little bit of weight She went several months where her focus was healthy exercise with adequate nutrition and so the focus was basically on building fitness, building endurance, building in strength training, and we completely let go of burning fat. She looked great. This was like she felt like she could do better, and ultimately she could, but it wasn’t the way that she had been going about it. She ultimately found that by repairing those for her baseline hormones of being in constant calorie deficit, in constant forcing her body, in constant frustration with her body, she was able to slowly repair that trust that her body had in her. If you think about it this way, if the body thinks that there’s no food because you’re constantly starving it, she was able to come to terms with, This is where I’m currently at. Where I’m currently at is actually great. Where I’m currently at is being able to love what my body is able to do. As she continued, she began to get really excited about and focused on what her endurance abilities were, what her lifting capabilities were, how strong and capable she felt.

She started to do extracurricular type things where she would get out and do activities that used her fitness, and so she got to fully enjoy what she was doing rather than just having a vision of how she needed to look in the mirror. It became, what do you want to be able to enjoy that your body is going to be able to allow you to do. Then over time, she was able to do very slight calorie deficits and had actually a very different goal of where she wanted her body fat percentage to be and why. She found that there was a sweet spot. It was It wasn’t quite where she had thought she was going to need her sweet spot to be, but she found a sweet spot where she was able to actually have a lot easier time managing her insulin effect, where she was able to eat a wider variety of foods, where the amount didn’t matter as much, so she didn’t have to be as strict about counting. She was able to enjoy a wider variety of foods and didn’t have to be as strict about what she was eating as far as her insulin and her glycemic control as well as the calories. She was able to have a general, this is how I eat, and then have a little bit of flexibility in that as well to maintain her health goals. Where does this apply to everyone with different goals, different journeys? What do I want you to take away from today’s episode?

Well, first of all, when you know what your goal is and you feel like you keep hitting a plateau, you feel like you keep hitting the same wall, you’ve tried things and they don’t work, you’ve taken the advice of someone and it doesn’t work, What do you do next? How do you avoid just following into this pit of despair where just nothing’s going to work for me? I must have a specific situation with my PCOS that’s different from everybody else out there that’s having success in repairing their hormones and creating health for their PCOS. Mine just must be different. When we hit a plateau, when we hit a wall, what our body is telling us is, That’s not what I need. I can’t work with that. Oftentimes, and this is a side note, but where I don’t love fertility treatment is I feel like in the wrong circumstances, they are just an outside force trying to force our bodies further.

In some places, we do need to push ourselves. There’s a lot of places in life where if we want to be successful and we want to grow and we want to expand our horizons and learn new things, and even through creativity, learn new skills and new hobbies, we have to push ourselves, go outside of our comfort zone, making new friends. Sometimes we have to go outside of our comfort zone. There’s so many places in life where going outside of our comfort zone or pushing ourselves a little bit is a positive but when it comes to our fertility, our reproductive hormones, our deep root cause metabolic hormones that are part of the PCOS root causes, these are fragile systems. They’re like your internal engines that allow you to be however healthy you want to be. When we are ignoring their needs and we are just saying push harder, and they’re saying, I am spread too thin, or that’s not how I work, or whatever it is that you’re pushing and they’re not responding the way that we want, we need to relook at what’s going on. This is essentially where the PCOS Root Cause quiz comes in. I want you to discover what’s going on under the surface and what’s going on with your PCOS Root Cause hormones. Then I want you to learn about your root cause hormones and what to do about them. While doing that, the part where Zoe’s story becomes really impactful to me, and I hope becomes an inspiration to you, is learning to allow yourself to become part of that journey in a way where you are embracing yourself where you’re at, you are embracing what goal you have for yourself. It doesn’t have to be so clearly defined. Zoe has changed. She realized that, Oh, there is a a whole different way that works for my body and still gets me to where I want to go and how I want to be and how I want to see myself and what I want to achieve and what I want to enjoy and how I want my body to help me function in life than she originally visioned, and it was was better than what she visioned, and she was able to pass those roadblocks that had been her stumbling places before but she came at it from an entirely different angle, from a place of caring about her body rather than being frustrated with where it was letting her down.

An example of where I see this trip women up a lot when they’re looking at their fertility is that there’s nothing more set in stone, difficult to be flexible on, or that trips us up more as women than having an idea in our mind of when we were going to start a family and then being told it’s not going to happen in that time frame but when we can embrace that our body is needing some help first, and the time frame is going to need to be adjustable, and when we can accept that and become a little bit flexible with that time frame, the amount of pressure that we take off of ourselves and the amount of healing that we can allow is huge. Now, I’m not saying relax and you’ll get pregnant. That’s not what I’m saying. So don’t hear that, please. What I’m saying is that when we have this thing, I’m supposed to ovulate next Wednesday, that’s what my charts are seeing. That’s if I march out what has happened before, that’s what should be happening It’s happening, and so I need to do everything right between now and Wednesday, and then when it doesn’t happen, we’re devastated.

What this looks like more is instead of having a specific date on the calendar of Wednesday, I need to ovulate. If we look at, Okay, my body is struggling to have a regular cycle. It’s struggling to ovulate. How can I support my body to, over the next several months, get closer to that goal? That has a very different push on our body. Instead of all of a sudden, you will ovulate, body. All of a sudden, we are calming down and saying, Okay, ovulation is still the goal. Fertility and pregnancy is still the goal but I’m accepting and honoring the fact of where my body’s at. I’m also maintaining the positive view of my body that it is able to get where I need it to go and where I’m wanting it to go, but it’s needing my help. It’s needing me to create that environment. It’s needing me to understand it. Understanding it is another way of saying discovering those root cause areas that our body needs help. Then as we create those, we may not be able to provide those overnight. They may take us a few months to figure out how to provide those to our body.

Then our body needs time to recover and calm down and to get back in a rhythm. It takes a little while. As we accept that, we no longer are working against our body. We’re working with our body and when we work with our body and we find that intersection between, we still have goals, we still have dreams, we still have visions of growing and becoming more, but we are also able to see where we’re currently at, honor that, celebrate that, and see all the good that we’re able to do, and then with that energy, move forward to what we want.

So I hope that that is helpful for many of you. I know I get a lot of DMs of frustration, of feeling stuck. Of course, if you are feeling stuck and you would like assistance, I do work with women one-on-one as well as in group programs. If you have any questions, please feel free to connect with me over on Instagram. You can find me @nourishedtohealthy, and until next time, bye for now.

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About Show

Welcome to The PCOS Repair Podcast!

I’m Ashlene Korcek, and each week I’ll be sharing the latest findings on PCOS and how to make practical health changes to your lifestyle to repair your PCOS at the root cause.

If you’re struggling with PCOS, know that you’re not alone. In fact, it’s estimated that one in ten women have PCOS. But the good news is that there is a lot we can do to manage our symptoms and live healthy, happy lives.

So whether you’re looking for tips on nutrition, exercise, supplements, or mental health, you’ll find it all here on The PCOS Repair Podcast. Ready to get started? Hit subscribe now

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

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The Root Cause of Hormone and Nutritional Disturbances

What you’ll learn in this episode

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Understanding Hormonal and Nutritional Disturbances:

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Hormonal Chaos 

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Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

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Read The Full Episode Transcript Here

All righty, guys. This is our last week of the mini-series about PCOS root causes and diving into what is going on in each and every one of them. Today, we’re going to get into the, again, my terminology, guys, that this is the hormone and nutritional disturbance root cause. We’re going to get into exactly what’s going on there and why it’s named this way as we dive in to today’s episode.

You’re listening to the PCOS Repair podcast, where we explore the ins and outs of PCOS and how to repair the imbalances in our hormones naturally with a little medical help sprinkled in. Hi, I’m Ashlene Korcek, and with many years of medical and personal experience with polycystic ovarian syndrome, it is my joy to watch women reverse their PCOS as they learn to nourish their body in a whole new way. With the power of our beliefs, our mindset, and our environment, and the understanding of our genetics, we can heal at the root cause.

Welcome back to today’s episode of the PCOS Repair podcast where we’re diving into hormone and nutritional disturbance root cause. When we think back about the pyramid, and again, if you haven’t listened to the last couple of episodes, make sure you do so. We talk about the pyramid and all sorts of things with terminology so that you’ll be able to better understand what’s going on in today’s episode. But this is the very top of the pyramid as we get towards the actual symptoms of PCOS. Some people will find that they have this going on, but there’s so much going on below it, we don’t call this your root cause. So pretty much everyone that’s having symptoms of PCOS is having some hormonal disturbance but sometimes this occurs secondarily to not really having a lot of other root causes, or maybe you have all three root causes, but fairly mildly. Where we see this particular root cause show up is where someone has been, maybe without knowing it, has found their way of dealing with PCOS. They have found their unique way of managing their weight, managing their health, and they’re doing great. Then maybe they go on a birth control or they change birth control or they come off of birth control, or maybe they have some other severe illness or some big event that the body deems a big event.

You may think stopping the birth control pill wasn’t a big event, but your body felt like it was a big event. Then chaos ensues and we start to have a downward spiral and some women, they catch it pretty quickly and then when we start working together, they’re still at this phase. Some people this started and just continue to where then the insulin became a problem and then they’re stressing about all of it, and everything’s becoming harder, life’s becoming harder because of all of this. So the stress response becomes more of a thing, and the other root causes begin to grow. The inflammation begins to grow because, again, all of these symptoms lead back to increasing inflammation, and all of these root causes increase the inflammation because it’s all interconnected. That makes it seem messy, I like to think about it as PCOS being a spiral. When we are improving our health, when we’re nourishing our body, when we’re getting the sleep that we need, and we’re doing all the things that care for the root causes that are in play for us at that very time because they change, sometimes there’s one, sometimes there’s multiple, so it changes. It’s not a fixed thing.

As our root causes change, so does our care for our body but if we’re caring for our body, we’re going to start seeing that we arrest that downward spiral and we start to spiral upwards. Then maybe we go on a vacation or life becomes stressful and busy and we stop being as good at it and we’re managing for a little while. We’re hanging in there, we’re living on borrowed time and we feel like we’re still keeping it together. Then all of a sudden, it gets ahead of us and we start to see that downward spiral. That can happen in small ways or big ways, depending on how knowledgeable you are about what your body is needing and about your root causes, which brings us back to why we’re doing this mini-series is to help you become more knowledgeable about the root causes so that you can understand your body better.

Okay, so what’s going on? That’s a broad overview, but what’s going on when it comes to a hormonal or nutritional disturbance? This is where I do tend to see, now this is not 100%, but I do tend to see this 99% of the time in women who are struggling post-birth control. Now, some people were struggling with things like insulin and stress and inflammation before they went off of birth control. Yes, their hormones go into chaos and dysregulation, secondarily to going off of birth control, but it was already there deeper. Some women were actually doing quite well prior to going off of birth control, and that just threw them into chaotic habit. I will use my example to shed some light on how this looks, practically speaking. I have always had insulin-heavy root causes of my PCOS. Insulin effect has been part of my journey since 13. I was one of those women that just was I came from a very healthy family. We ate very healthy. It was very obvious to me that if I am gaining weight uncontrollably and I’m eating very healthy, I don’t know how you could eat much healthier than my family. We did eat dessert occasionally and things like that, but my mom cooked very healthy, and we were fairly active. You’re looking at this going, I’m probably above the average here, and I’m really struggling and heavier than all my peers. I’m struggling more than all my peers. Something’s not quite right here.

I learned pretty early without having words for it, without having technical terms, without knowing the pathophysiology, I learned that intermittent fasting worked really well for me. There was times where my weight was doing fine, and then there would be times where I would start that, like we were just talking about, downward spiral. What would work very well for me in those instances, because unbeknownst to me at the time, I had insulin effect, root cause, PCOS going on. Just a little bit of decreasing my eating window and not eating after about 4:00 PM was excellent for me. I could just eat an early dinner and then not eat anything all evening and continue my regular exercise, continue my regular healthy diet, and that would arrest my downward spiral. That was a lot easier when I was 13. As I got older, it’s definitely gotten more complicated and more convoluted, but I was able to coast on that for a long time. I got to the point where my husband and I were ready to start a family, and I went off of birth control. I had the IUD at the time, and the Mirena one, the one that had a little bit of progesterone with it, and specifically, progestin, not to be confused with bioidentical progesterone, but the synthetic progestin.

In that situation, your hormones have been subdued, and all of a sudden, everything’s taken away and your body’s sitting there going, I think they’re expecting me to do something. It goes into chaos. It doesn’t have a rhythm, it doesn’t know where it’s at, and it just starts going into chaotic mode. That lasted for me for about a year. During that year, I gained 40 pounds in the first two months. Now, not only am I dealing with this chaotic hormonal birth control mess, now we’re adding in there the degree of insulin effect coming from excess weight, also the inflammation coming from excess weight, as well as I was definitely stressed about all this, but I don’t think at that time in my life stress was playing as big a role in my PCOS but then it really took diving into my eating and exercise to really address the insulin effect appropriately. As I began to do that, I was able to slow the downward spiral, to arrest the downward spiral, and slowly start getting it to spiral upward. Also, So at the same time, beginning to repair my cycle. So I went that year with.. I think I had… It was about every two months. So I was having about 45 to 66, I think was the longest I went, day cycles and those cycles were out of control. They weren’t super long, but it’s almost like I couldn’t leave the house because I was going to bleed through anything that I wore for those three days because it lasted… It was really 24 hours where it was super bad but it was really, really, really bad. I had always had heavy periods. I was pretty adept to handling a heavy period. These things were not like, hardly even a period. It was like, it was just crazy and that lasted for… In some ways, I was glad they weren’t coming every month, but we were trying to get pregnant. So whenever you’re tracking your cycle and it’s not coming out regular, it’s very disturbing. Over the course of that year, I finally was able to get those cycles regulated again, primarily through diet and exercise at that point in time in my life, although there’s been different times where other measures were needed. That’s where the hormonal disturbances can come in. Now, for some women, they don’t get thrown so heavily into the insulin effect, root cause of PCOS.

I, if you look at my history, had had it prior, and so that really rose up in the face of the hormonal chaos but some women, they’re managing all of those things pretty well, and everything Everything else seems fine, and they just cannot get their hormones to regulate. Oftentimes, that is a combination of the withdrawal of birth control. Also, it can be due to hormonal disturbances. The Western diet is really void of a lot of nutrients. Our very indoor living can be also a cause of some vitamin deficiencies, poor absorption due to certain other lifestyle factors can cause nutritional disturbances. Then also just being on hormonal birth control can deplete several of our nutritional stores. We need to make sure we’re getting all the things that we need because as soon as our body feels like something is not quite right. As soon as we feel like our body feels like we may be depleted in some way, it’s our fertility that gets turned off. If we want to have a regular cycle, if we’re trying to get pregnant, we need to really make it to our bodies that we are in a good place.

We have the resources we need. Our body is safe and healthy and ready to take on this challenge of having a baby. When it comes to our hormonal disturbances, that’s what’s going on with that root cause. It’s a little bit of the everything else seems fine, but we just can’t quite seem to get this natural rhythm. Some women have this by itself. Some women have this very closely secondarily as their secondary root cause. Basically, as we address this, we start to really address, how do we recreate that cycle, which hormones are needing a little extra boost to begin to play off, to work nicely in unison. That brings me to the next thing that I want to touch on, which is not exactly part of the root causes, but is as we wrap up this mini-series, is something that becomes really important, and that is the cycle of the hormones in regards to your root causes. This really pertains to all All of your PCOS symptoms, but we’re going to talk about it from the standpoint of your cycle. If any of your hormones are unbalanced, any of the symptoms that you’re experiencing are going to worsen.

Everyone has their own concerns with their PCOS, their own goals of what they want to achieve with repairing their PCOS, and what exactly is going on under the surface that they need to address. What we’re talking about here, though, is how are these hormones, how do they play out to amplify or dampen each other. In a cycle, which is how they communicate, how are they worsening or improving? Because that’s going to have an impact on any of those PCOS symptoms. Whether or not pregnancy is your concern, whether or not your regular period is your concern, this all does play together to improve your surface symptoms. You’re probably beginning to notice here that everything is very connected and intertwined. It can cause a very vicious cycle, as we talked about the root causes and how they are intertwined between the stress hormone of cortisol to insulin to inflammation. Then as these superficial hormones, the ones towards the surface, that we typically think of with PCOS, like testosterone, LH, FSH, estrogen, and progesterone, these hormones all are intertwined with these as well. Then we have lifestyle factors such as food, stress, excess weight, and these all. They’re going to increase chronic inflammation.

They’re going to decrease your insulin sensitivity and make you more towards that spectrum of insulin resistance, leading to further weight gain and more inflammation. That’s an example of how the vicious cycle works, but it goes even beyond that. While food can definitely worsen the inflammation and the insulin effect, there’s always this other underlying problem of stress, and it can also be furthering the insulin effect and the inflammation and so forth. That’s working our way back down into the base of the pyramid. All of these factors, they’re intertwined, creating a downward spike, but they all essentially lead to the elevation in testosterone. As we talked about, there’s all sorts of different ways, and you can go back and listen to the other episodes of how each way does it, but they basically all elevate testosterone. As we talked about hormone and nutritional disturbances, this one is less about elevating the androgens, and it’s more about what’s going on when external forces created a hormonal storm at the surface, leading to imbalance in those reproductive hormones. There may be some aggravation from the root cause hormones, but this one’s a little bit more superficial, but we’re still dealing with this elevated testosterone.

So all of this still applies as we talk about what’s going on there. Okay, so This elevated testosterone slows our follicular development during the follicular phase. The first phase of our cycle, we start with our period, and then we have FSH, our follicular estimating hormone, is causing and telling one of our follicles on our ovaries to start to mature. It actually tells several to mature. Over the course of this phase, one wins out and becomes the dominant one, and that’s the one that then will hopefully mature and then be released in ovulation as an egg. The testosterone overrides the estrogen surge. The estrogen and testosterone balance is incorrect. The follicle doesn’t mature as far as it should. When we’re looking at the follicular phase dysfunction, we want estrogen to shine. Estrogen shines in a slightly lower glycemic index system than you’ll see later in the luteal phase. So estrogen does really well on a lower sugar, lower glycemic, lower carb phase and then as we mature that follicle, we need an LH surge. So testosterone slowly raises the LH and if your LH is elevated, it doesn’t allow for this big surge. The surge is what we call blunted, and ovulation won’t occur because your body doesn’t recognize this sharp peak in LH because it was elevated at baseline and so ovulation doesn’t occur. So even if it’s not overridden enough to stop ovulation, oftentimes the ovulation will be a little bit weak, and on the back side, the corpus luteum, so the lining of the uterus isn’t producing enough progesterone. There’s an inability to sustain a healthy pregnancy because your body needs that elevated progesterone until your body can take over, until the placenta can take over. So that elevated the progesterone is really important in those first couple of weeks.

This is how the root causes all play together. Subsequently, the more times we ovulate, the more we raise that progesterone. As we repair the cycle, the first step is really to get that ovulation to occur, with the ovulation, then the corpusludium gets nice and thick, and so then it will bleed like it should when the progesterone levels drop. If your progesterone levels are too low, they never drop but one of the best ways to elevate your progesterone is to just start having a cycle. Even a week ovulation is slowly increasing and improving your progesterone levels. Basically, the point here is that it’s all interconnected. As one thing improves, the next thing improves, and it brings more improvement throughout each aspect of what’s going on in those reproductive hormones, more towards the tip of the pyramid, as well as your They’re slowly working on those more deeper root cause hormones, and so they’re bringing their improvement up through the pyramid as well.

I know this can all be very, very, very confusing. I want to give you the first place to get started. The first place to get started is really to take that PCOS root cause quiz. It’s going to show you as far as what symptoms you’re having, even beyond your PCOS symptoms, but just daily symptoms, and what they would indicate is going on deeper in your root cause hormones that we I’ve been talking about here in this mini-series over the last few weeks. The next step is to start adjusting your lifestyle accordingly. Now, this is where things get complicated and isn’t something that’s a blanket statement, one size fits all. This is where you have to get to know your body as well as the information on how to address what your body is needing. The best ways to do that is to work with me one-on-one or to take one of my programs. If you want to learn more about that, I will include links to those in the show notes below but the first, first, first step is to really learn what’s going on in your root cause so that you can learn what your body is dealing with. Then the next step is what would we need to do to your lifestyle to help support what’s going on in your body and the root causes.

With that, this concludes our mini-series on what’s going on with the root causes and understanding them deeper and at a better level because there’s a lot of misconceptions of what’s going on under the surface of PCOS symptoms. Hopefully, these last few episodes have helped you to understand those more clearly. If you have any follow-up questions, you know where to find me. I’m over on Instagram @Nourishedtohealthy, and I look forward to continuing the conversation with you over there. Until next time. Bye for now.

Take The PCOS Root Cause Quiz

   What Do Your Symptoms Mean?

  Discover your current PCOS Root Cause

Start to reverse PCOS at the root cause. 

Results are not guaranteed. Please see Medical Disclaimer for more detail.

Similar Podcasts You Will Enjoy

Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

This episode explores the multifaceted role of Metformin in managing PCOS. Drawing from recent research and real-world experiences, it breaks down the benefits and challenges of using Metformin for PCOS treatment. Whether you’re considering starting Metformin or optimizing its use, this episode offers practical tips for managing side effects and making informed decisions that align with your health goals. Tune in to gain new perspectives and feel more confident in discussing Metformin with your healthcare provider.

Episode #121: Zoe’s Self-Love to PCOS Health Victory

Episode #121: Zoe’s Self-Love to PCOS Health Victory

In this episode of the PCOS Repair Podcast, you’ll hear the inspiring story of Zoe, who transformed her health and self-perception through body acceptance and self-love. Despite facing frustrating plateaus in her fitness journey, Zoe learned to work with her body rather than against it, ultimately finding balance in managing her PCOS symptoms. Tune in to discover how shifting your mindset and embracing where you are can lead to profound changes in both your health and self-image. Whether you’re struggling with PCOS symptoms or body image challenges, this episode offers valuable insights for achieving your health goals.

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

In this episode of the PCOS Repair Podcast, we conclude our root cause mini-series by focusing on the hormone and nutritional disturbance root cause. We explore how hormonal imbalances and nutritional deficiencies contribute to PCOS symptoms, especially after abrupt changes like stopping birth control. Learn how these disturbances, combined with insulin and inflammation, affect PCOS and discover practical strategies for managing your symptoms. Tune in to gain a comprehensive understanding of how to tackle PCOS from multiple angles and take control of your health journey.

About Show

Welcome to The PCOS Repair Podcast!

I’m Ashlene Korcek, and each week I’ll be sharing the latest findings on PCOS and how to make practical health changes to your lifestyle to repair your PCOS at the root cause.

If you’re struggling with PCOS, know that you’re not alone. In fact, it’s estimated that one in ten women have PCOS. But the good news is that there is a lot we can do to manage our symptoms and live healthy, happy lives.

So whether you’re looking for tips on nutrition, exercise, supplements, or mental health, you’ll find it all here on The PCOS Repair Podcast. Ready to get started? Hit subscribe now

Episode #119: The Root Cause of Inflammation

Episode #119: The Root Cause of Inflammation

Episode #119: The Root Cause of Inflammation

This post may contain affiliate links. Please read my disclosure and privacy policy.

The Root Cause of Inflammation

What you’ll learn in this episode

In this episode we’ll continue our deep dive into the root causes of PCOS with a focus on inflammation, a key player that often goes unrecognized. Listen now to explore how inflammation interacts with our bodies and exacerbates PCOS symptoms, as well as unravel the complexities of the hormonal feedback loops.

Understanding Inflammation’s Role in PCOS

In this episode, you will learn about inflammation’s impact on PCOS beyond the surface symptoms. I’ll explain how even without overt medical conditions, subtle ongoing inflammatory responses can intensify PCOS symptoms. This episode is crucial for anyone struggling to connect their lifestyle and environmental influences to improve their PCOS symptoms.

Lifestyle Factors and Inflammatory Responses

Explore how everyday choices can inadvertently invite inflammatory responses that worsen PCOS symptoms. This episode provides insights into how diet, stress, and environmental toxins play roles in inflammation. More importantly, it offers practical advice on mitigating these effects through informed lifestyle changes.

Navigating Misconceptions and Medical Advice

If you’ve been struggling with limited medical support for your PCOS, this episode aims to clarify common misconceptions about inflammation and its indicators. You’ll gain insight into the critical importance of medical options within the specific context of PCOS, advocating for a more nuanced and informed approach to managing the condition.

Stay tuned and subscribe to ensure you don’t miss out on invaluable insights in this mini-ongoing series designed to empower you in your fight against PCOS. Until next time, take care and nurture your health!

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

rate the podcast

Spread the Awareness

If you have found this podcast helpful please take just a moment to rate it and leave a review. This helps apple, spotify or whichever platform you use know to share this podcast with other women. I truely appreciate your help supporting as many women as possible ♥

Read The Full Episode Transcript Here

In the last episode, we dove into the insulin effect and how that root cause is so impactful and such a big part of PCOS, but there are so many myths around it. And in this episode, we’re going to get into the next root cause as we move up the pyramid of PCOS root causes and talk about inflammation. So without further ado, let’s dive in. 

You’re listening to the PCOS Repair podcast, where we explore the ins and outs of PCOS and how to repair the imbalances in your hormones naturally with a little medical help sprinkled in. Hi, I’m Ashlene Korcek, and with many years of medical and personal experience with polycystic ovarian syndrome, it is my joy to watch women reverse their PCOS as they learn to nourish their body in a whole new way. With the power of our beliefs, our mindset, and our environment, and the understanding of our genetics, we can heal at the root cause.

Welcome back to the PCOS Repair podcast, where today we are continuing our mini-series about hormones and the root causes of PCOS and their connection to how you experience things in your environment and your Lifestyle and how all of these things are very intertwined to create the symptoms that you are experiencing on the surface. As we dive into today’s topic of inflammation, I just want to recap a few things. One, if you haven’t listened to the last couple of episodes, make sure you do so because they all build off of each other. Then secondly, this terminology is all my own. Yes, it has words that you hear in other medical office, maybe that you’ve googled, that you’ve heard on social media when it comes to PCOS but when I talk about the root causes, these are my a specific terminology because the way I group things is a little different than other people. It’s because we’re working in a pyramid of hierarchy of where do we really need to address first and how do we move things up, and then also recognizing where your body is struggling the most in that ascension, as well as really truly naming what the problem is.

We saw this last week if you review last week’s episode in the Insulin Effect. It really emphasizes the fact that we’re not talking about insulin resistance. Your PCOS doesn’t show up as soon as you develop insulin resistance or type 2 diabetes. The actual production of insulin on a routine dietary meal or snack basis is enough to elevate those androgens, especially if you are consistently over time having meals that are highly elevating that insulin. The genetic component that comes into that, and also we’ll talk about this in regards to inflammation, is that women with PCOS have genetics that just make them more sensitive. For someone else who could just wake up in the morning and eat a bunch of fruit without anything else, for someone with PCOS who’s highly sensitive. Again, our genetics are going to vary. Some people are going to be really sensitive, some people are going to be more sensitive than someone who does not have PCOS but that someone who’s really, really sensitive, a handful of grapes in the morning be enough to shoot their blood sugar way up to 175. I’ve had that happen to me before. You’re like, Oh, my gosh, I only eat 10 grapes.

Now, if I eat that after exercise, if I eat that in other context of my day, it may not have that drastic effect but on this particular morning, I was wearing my continuous glucose monitor, so I was able to see that just a small handful of grapes while I was getting ready for something for the schools for my kids. It was like I was just washing and doing grapes and gave to my kids for breakfast. I also ate some, hadn’t eaten anything else. So empty stomach, handful of grapes, shot my glucose up. You can only imagine what that would do to my insulin. My insulin is going to mirror what my glucose does. If my glucose all of a sudden goes really high, my insulin is going to go, Oh, my goodness, we have work to do. It’s going to secrete a lot of insulin into your system, or your pancreas is going to secrete a lot of insulin into your system. If you’re constantly doing that, your ovaries are being constantly bombarded with the signal of insulin to produce more androgens. This is why, and I go back to this over and over, because this is a concept that most women with PCOS are very confused by, thanks to the terminology we use in medicine and how we diagnose things and how we have a spectrum disease that we don’t call a problem until it reaches a certain point.

Well, it’s been growing in problem the entire way. We’ve just been ignoring it until it reaches a certain marker, and now we call it a problem. This is why I refer to things as the insulin effect but again, long story to try to illustrate. This is my terminology. It’s not necessarily what you’re going to find in scientific journals or textbooks. Doctors not going to know what you’re talking about when you use my terminology, but it’s all based in the same science and pathophysiology that I learned in physician assistance school and the doctors learned in medical school, but it’s just different ways of labeling things for our own conversation purposes here on the podcast and in my courses and when I work with women. What we’re actually talking about is a lot more clear that we’re just talking about insulin in general. We’re not talking about whether or not you’ve reached a specific point on a spectrum of disease. The other thing that I want to point out is the pyramid. We’ve been reviewing the pyramid of root causes. That’s what this mini-series is all about. If you’ve missed any of the previous last now three episodes, go back and listen to those because this all builds off of each other.

In the pyramid of root causes, this is what’s going on in all humans, probably animals, but I’m not as familiar with animal physiology and anatomy, but for humans, we all have this pyramid of hormonal response. When it comes to PCOS, we see this happen at a younger age, at an age where other people are not struggling with weight, where other women are not struggling with fertility issues, we’re seeing this become more of a problem, but this is the same reason why, as a culture, we tend to be heavier in this generation than in previous generations. It’s the same pyramid of hormones, but when it comes to PCOS, our genetics make us even more sensitive to our environment, so we see this in heightened response. At the base of our pyramid, we have cortisol. As we move up the pyramid, we have insulin. As we move up the pyramid further, we have inflammation, which is what we’re going to be talking about today. The reason the inflammation is a little higher in the pyramid is two things. One, it be caused by secondary medical conditions, we’ll talk about that. Then also, it can actually be a result of what’s happening below it.

As we start to see high levels of stress, if those high levels of stress are chronically, consistently present in our life, our body is frequently perceiving stress and again, we talk about what constitutes as perceiving stress and what constitutes as stress in two episodes ago. So make sure you go listen to that one, but as we chronically dealing with that or chronically dealing with high levels of insulin circulating our system, again, not insulin resistance, not diabetes, but just high levels of constant insulin, those states create inflammation. Stress creates inflammation, High insulin response or high exposure to insulin because it’s in our system a lot creates inflammation. Excess body weight creates inflammation. PCOS, just the baseline of the genetics of PCOS, creates a higher tendency towards inflammation. Then you can add into that our environment. We can add into that other medical conditions. We’ll come back to environment in a second, but other medical conditions that we may be dealing with can be something like asthma, allergies, skin disorders such as psoriasis. We can have autoimmune disorders such as lupus or rheumatoid arthritis. There’s all sorts of inflammatory disorders. When we combine those, they’re not mutually exclusive, and they’re also not necessarily always found together but as humans, we get to have the whole array of how things are basically aligned in our genetics. We can end up with PCOS and an autoimmune disorder, and they can be completely separate, but at the same time, play off each other.

When it comes to chronic disorders, the more that we can manage those to reduce their inflammatory response. If we keep ourselves less inflamed in regards to those, typically our PCOS improves to some degree as well. Although, remember, they are not connected. Having asthma and having PCOS is not connected, but if we have uncontrolled asthma and we’re having increased constant pulmonary, so lung inflammation and chronically coughing or having uncontrolled asthma, That is going to increase our base inflammation. That base inflammation chronically is going to worsen our PCOS. Typically, the other direction is less true, although being overweight because our PCOS is uncontrolled and unmanaged can worsen our asthma. There is some crossover the other way as well in certain situations. But typically, if we can manage our inflammatory disorders such as eczema, psoriasis, asthma, rheumatoid arthritis, lupus, all of those, we typically start to see that our PCOS is a little less vengeful. It doesn’t go away because there may be other components. There may be deeper root causes that may be going on. There may be other things going on as well, but we see that it fights us less. Our body will fight us less if our inflammation is under control.

Then we have other forms of inflammation. These are ones that we invite in, oftentimes unknowingly, through our lifestyle. We already talked about basically dietary can have a huge insulin effect. Our stress and our sleep habits can have a huge cortisol effect. Other things, we can bring in toxins that are inflammatory and disrupting our endocrine system. We can have just other foods that are bringing in a lot of toxic or inflammatory properties that we’re eating besides just raising our insulin. We can have pollutants or poor water sources, poor air sources, etc. You can see there’s lots of things that we can be coming in contact with in our environment, and that’s by no means an exhaustive list, but gives you some of the main categories that can be bringing inflammation into our bodies.

That leads to the question of why is inflammation a problem for PCOS? What is going on where we have to be concerned about inflammation when it comes to PCOS. Basically, when you have a small amount of inflammation in the body, so think acute injury, you cut your finger or you got a cat scratch on your finger and it swells up because you’ve got maybe some microbes in there and there’s this lesion, and your body is trying to protect the rest of your body from being exposed to whatever is going on in this injury. You’ll find that there’s some local redness and irritation. It can get pretty extreme sometimes. Maybe it gets so extreme that it starts to get infected, which is why there’s inflammation there actually. The infection is a secondary response that’s happening, and the inflammation is occurring to help protect your body from being as vulnerable to that point of infection there, but the inflammation is going to clear on its own. What we’re talking about here in this episode is chronic inflammation. You can do lab markers to show chronic inflammation. You can feel really tired, lethargic, weighed down. You can feel puffy. You can feel just like that brain fog can be many, many things.

It can be related to stress and blood sugar as well, but it can also be related to inflammation. If you take the root cause quiz, it helps to differentiate what symptoms are meaning what and gives a little bit bigger picture on that. I will link that in the show notes as well. But when you have this moderate to high level of constant or what we say chronic inflammation in the body, it is working on our ovaries directly to produce more androgens. So similar to insulin, having high levels of inflammation tell our body to produce more androgens, leading to more symptoms of PCOS. So you can see where if you were having stress and inflammation and eating in a way that was creating higher levels of insulin, you’re going to be hitting your ovaries and things from all sides to just be pumping out those androgens. As we start to calm the one that is the most prominent, so that’s what we’re looking at when we take the PCOS root cause quiz is that while, yes, You may have every single one of these root causes in some degree, which is the one that’s contributing the most to that androgen production?

Let’s focus on that one first. There’s a vicious cycle goes between them all. Maybe as we address the one that is the biggest problem, sometimes the other ones ease up significantly, even just with addressing that one. Otherwise, we can go in and do an additional little bit of assistance in our lifestyle to help the other two or other one, if the other as needed. What we see is that we start to feel so much better, which by feeling even just a little bit better, allows us to give that much more care and nurturing to our body to, again, improve our symptoms and to reduce those negative effects. That’s how inflammation works on the body. Having a constant low, medium, or high grade of chronic inflammation is in the same degree. So mild, moderate, or a heavy amount of inflammation is going to tell those ovaries to produce a small, medium, or larger amount of excess androgens. Just to recap, androgens basically means testosterone. We’re raising our testosterone level, which, as we talked about in the previous episode, raises your LH, which messes with your cycle, messes with your other hormones, messes with symptoms. Having high testosterone or LH levels that are off are the reasons for things like acne, Loss of hair on the body, loss of hair on the head, period problems, fatigue, energy problems, sleep problems, and the list of PCOS symptoms goes on and on.

As we wrap up today’s episode, again, go back and listen to the previous episodes. If you have missed those, they all help paint the picture of what’s going on here in your root causes. If you have found this mini-series helpful, please be sure to hit the subscribe button because we have another episode coming next week where we’re going to be talking about a higher level of root cause that is a little bit less clear. I think that a lot of people, especially when they’re younger, are dealing with when things haven’t gotten so far out of hand in their deeper root causes. What is going on there, how to think about it, how to understand it, and how to get a better glimpse and understanding of what’s happening in your body, specifically. Be sure to hit the subscribe button so that you’re notified when that episode becomes available. Until next time, if you have any questions, I’d love to connect with you over on Instagram. You can find me @Nourishedtohealthy. Again, I look forward to hearing from you over there. Until next time. Bye for now.

Take The PCOS Root Cause Quiz

   What Do Your Symptoms Mean?

  Discover your current PCOS Root Cause

Start to reverse PCOS at the root cause. 

Results are not guaranteed. Please see Medical Disclaimer for more detail.

Similar Podcasts You Will Enjoy

Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

Episode #122: Scientific Spotlight: Journal Article Review on Metformin and PCOS

This episode explores the multifaceted role of Metformin in managing PCOS. Drawing from recent research and real-world experiences, it breaks down the benefits and challenges of using Metformin for PCOS treatment. Whether you’re considering starting Metformin or optimizing its use, this episode offers practical tips for managing side effects and making informed decisions that align with your health goals. Tune in to gain new perspectives and feel more confident in discussing Metformin with your healthcare provider.

Episode #121: Zoe’s Self-Love to PCOS Health Victory

Episode #121: Zoe’s Self-Love to PCOS Health Victory

In this episode of the PCOS Repair Podcast, you’ll hear the inspiring story of Zoe, who transformed her health and self-perception through body acceptance and self-love. Despite facing frustrating plateaus in her fitness journey, Zoe learned to work with her body rather than against it, ultimately finding balance in managing her PCOS symptoms. Tune in to discover how shifting your mindset and embracing where you are can lead to profound changes in both your health and self-image. Whether you’re struggling with PCOS symptoms or body image challenges, this episode offers valuable insights for achieving your health goals.

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

Episode #120: The Root Cause of Hormone and Nutritional Disturbances

In this episode of the PCOS Repair Podcast, we conclude our root cause mini-series by focusing on the hormone and nutritional disturbance root cause. We explore how hormonal imbalances and nutritional deficiencies contribute to PCOS symptoms, especially after abrupt changes like stopping birth control. Learn how these disturbances, combined with insulin and inflammation, affect PCOS and discover practical strategies for managing your symptoms. Tune in to gain a comprehensive understanding of how to tackle PCOS from multiple angles and take control of your health journey.

About Show

Welcome to The PCOS Repair Podcast!

I’m Ashlene Korcek, and each week I’ll be sharing the latest findings on PCOS and how to make practical health changes to your lifestyle to repair your PCOS at the root cause.

If you’re struggling with PCOS, know that you’re not alone. In fact, it’s estimated that one in ten women have PCOS. But the good news is that there is a lot we can do to manage our symptoms and live healthy, happy lives.

So whether you’re looking for tips on nutrition, exercise, supplements, or mental health, you’ll find it all here on The PCOS Repair Podcast. Ready to get started? Hit subscribe now

Episode #118: The Insulin Effect Root Cause

Episode #118: The Insulin Effect Root Cause

Episode #118: The Insulin Effect Root Cause

This post may contain affiliate links. Please read my disclosure and privacy policy.

The Insulin Effect Root Cause

What you’ll learn in this episode

In this episode, part of our ongoing mini-series on PCOS root causes, we delve deep into the insulin effect—how it uniquely impacts PCOS beyond traditional notions of insulin resistance. Learn the subtleties of insulin’s role and its broad implications, regardless of routine lab results.

The Insulin Effect  

Discover the concept of the “insulin effect” which extends beyond classic insulin resistance to influence PCOS symptoms through less noticeable mechanisms. Learn how normal insulin activity might still provoke PCOS symptoms by stimulating the ovaries to produce excess androgens, even when bloodwork appears normal.

Medical Misconceptions  

Learn the common disconnect between standard medical testing and the real-world implications of insulin’s impact on the body. Understand why typical lab results might not fully capture the extent of insulin-related issues and what that means for managing PCOS.

Influence of Lifestyle on Insulin Sensitivity  

Examine how modern lifestyle choices—like diet and stress levels—play a significant role in magnifying the insulin effect. Get actionable advice on modifying diet and lifestyle to better manage insulin levels and reduce its impact on PCOS symptoms. Discover how lifestyle adjustments can have such a tremendous impact on PCOS health. 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

rate the podcast

Spread the Awareness

If you have found this podcast helpful please take just a moment to rate it and leave a review. This helps apple, spotify or whichever platform you use know to share this podcast with other women. I truely appreciate your help supporting as many women as possible ♥

Read The Full Episode Transcript Here

When insulin is circulating in our bloodstream, it stimulates the ovaries to produce excess androgens. The big one is testosterone, thereby worsening our PCOS symptoms. I get so many questions about insulin and insulin resistance, and am I really having a problem with insulin because my doctor said my labs look fine. So In today’s episode, we are going to continue the mini-series about root causes, and we’re going to dive deeper into the root cause of the insulin effect. Today, we’re going to be diving into the root cause that I call the insulin effect and how it affects PCOS. So let’s get started.

You’re listening to the PCOS Repair podcast, where we explore the ins and outs of PCOS and how to repair the imbalances in your hormones naturally with a little medical help sprinkled in. Hi, I’m Ashlene Korcek, and with many years of medical and personal experience with polycystic ovarian syndrome, it is my joy to watch women reverse their PCOS as they learn to nourish their body in a whole new way. With the power of our beliefs, our mindset, and our environment, and the understanding of our genetics, we can heal at the root cause.

Welcome back to the PCOS Repair podcast, where today we’re diving into the root cause of the insulin effect. Now, before we dive in, I want to remind you that we’re in the middle of a mini-series. If you haven’t listened to specifically two episodes ago, number 116, I would go back and do that. It gives an overview of how all of the root causes work together and what we’re talking about with the pyramid of the base root causes and how they work up the pyramid to develop and worsen or repair our PCOS symptoms. I would recommend, if you haven’t or if it’s been a while, to go back and listen to that episode. I will link them all in the show notes.

Now, my terminology, the insulin effect, this is my terminology. It’s my way of trying to describe that it’s not necessarily insulin resistant or diabetic that creates the problem. You can be thin and have the insulin effect. You can be completely and totally normal with your hemoglobin A1c, your fasting insulin, your fasting glucose, your glucose tolerance test even, and still have the insulin effect going on in your PCOS. That’s what we’re going to dive into today is the why that can be happening, what is that creating, how is that creating a problem for PCOS, and just diving into better understanding all about the insulin effect.

Research has shown, and this is where so many physicians bring up insulin and test your insulin because research has shown that more than 70 20% of women with PCOS have insulin resistance. A huge amount of them have full-blown insulin resistance. As we find more and more women are being diagnosed with PCOS, I think that’s probably actually less and less true. Historically, PCOS was probably underdiagnosed. When I was diagnosed with PCOS, they were thinking maybe as many as 1 in 10 women had PCOS of reproductive age. Now, I’ve heard statistics where it’s looking like there may be more like one in six. I think there’s a combination here going on of one, more people are being correctly diagnosed, or as the awareness grows, women are going in and asking, and so more women are being diagnosed. But I also think that the lifestyle of the busy and prepared food, packaged food, fast food, eating out, eating on the go, all of the things that go with a fast-paced lifestyle are creating more and more tendency towards developing PCOS than before. Maybe it was underdiagnosed before because symptoms weren’t arising. People were being able to combat that with a relatively healthy lifestyle.

But now it’s getting more and more difficult to determine what’s a healthy lifestyle, what’s not causing inflammation. A lot of the things that we’re doing are affecting our cortisol, so our base hormone, our insulin, that next hormone up the pyramid, and then also our inflammation status. We’ll get into that one next week. Okay, so let’s first talk about when our labs are normal, does that mean that we have an insulin problem or not? Many doctors are like, Insulin seems fine right now. Your blood sugar seems fine right now. Perhaps metformin would be helpful, so they may still offer something like that. But for the most part, they say that’s not really your problem. I want to dispel that myth right now and say insulin is definitely still an important factor in PCOS health. Because whether Whether or not insulin is even your primary root cause or you’re having any issues with your labs, I want you to start with looking at the fact that our insulin health and our blood sugar health is on a spectrum. On one end of the spectrum, we have insulin health. Here, one, of course, our labs are going to be normal, but also our insulin response is going to be normal.

What this would look like is we eat food. Whatever food, whether it’s a high glycemic index, meaning it’s going to require a fair amount of insulin Say we eat chocolate cake. We’ll use chocolate cake as our example across the board. If our insulin is really healthy and we are otherwise eating pretty healthy, and on occasion, we have something like chocolate cake. We eat some chocolate cake, we have a really healthy blood sugar and insulin response. We eat that chocolate cake, our blood sugar rises appropriately, and our insulin recognizes that rise in blood sugar, or our pancreas recognizes that rise in blood sugar, it releases the insulin needed to send that blood sugar where it’s supposed to go into the cells of our body, into our muscle cells, into all the different cells of our body so that our body gets energy so that our body can function and survive. As we move along the spectrum, our insulin becomes a little bit annoyed at being summoned so much. If we’re constantly eating sugary foods, things that have high glycemic index, so maybe even if it’s not sweet, like potato chips, they’re still raising our blood sugar significantly.

They’re a very refined carbohydrate. We usually eat them in large amounts, and they’re pretty easy to eat, so we eat them pretty quickly. The combination of volume glycemic index, so how readily available is that sugar in the How rarely does it break down to sugar? Even if it’s, like I said, a salty food, it can still, like potato chips, break down into blood sugar very quickly. We get this high velocity impact of a large magnitude, so a large volume of blood sugar. That constantly doing that, our pancreas gets worn out. It starts to go, Really, guys? It starts to get frustrated where it may wait a little longer or it may just flood it with too much. It starts to become less and less precise. Then what happens is, is as we become more and more resistant, our cells actually are what become resistant. Our muscle cells, our other cells, they get We just ate, and they start to be resistant and they’re like, Yeah, insulin. We heard you before. They don’t listen very well. Insulin starts pounding on their doors. It just starts pounding on the doors and it starts sending out more insulin because the blood sugar is not going down, and so it puts more insulin into the system than even the foods that you ate would typically have required back when you had a healthy insulin response.

Then we start moving down the spectrum, and as that continues, we finally cross a threshold where the amount of blood sugar that’s in your system compared to the amount of insulin that’s required to get that blood sugar into the cells where it belongs has reached the resistant threshold on laboratory values. Basically, what that’s going to look like is your blood sugar is always too high because your insulin is not working very well. But your insulin is also going to be be high because it’s trying to, as it’s not heard, it’s putting more insulin into your system to try to be heard. It’s like it’s starting to try to shout at your cells. Take the glucose, take the glucose. It’s shouting at your cells and It’s rising in volume compared to what you ate. Looking back at the chocolate cake as we progress along this spectrum, one, you used to eat chocolate cake. It used to have an appropriate blood sugar response. Your pancreas would send out an appropriate amount of and your cells would quickly and happily respond to accepting the blood sugar. Then over time, as this became more continuous, as this happened more frequently, your cells started to not listen.

Have you ever had someone talk to you and they repeat themselves, repeat themselves, tell the same story, and at some point you start tuning out? Maybe you missed something that was different that they said this time because you’ve heard the same thing so many times that you stop listening. That’s what happens with your cells as they hear this so often and they start becoming a little bit, what we could say, resistant. At some point, that resistance gets large enough that you cross over the threshold of now in the medical community, we recognize it as insulin resistance. Now, there is a period of you were in good health, and then there’s a period of health decline before you actually reach the point of where we label it resistance. It’s a spectrum. Then from that resistance, what happens is that your insulin will actually start shutting down altogether. Well, then it increases and increases until you reach the type 2 diabetic standpoint. Then as your type 2 diabetes continues, you’ll actually reach a point where your insulin gives out altogether and says, Forget this, nobody’s listening to me anyway. Then that’s when the type 2 diabetics actually have to start injecting themselves with insulin.

Type 1 diabetics need it from the very beginning. Because they have insulin problem from the very beginning. When healthy individuals develop type 2 diabetes and resistance, it’s because over time, our bodies have repeatedly encountered too much blood sugar, too much insulin, too much blood sugar, too much insulin, to where we’ve stopped listening very well to the response that our body is trying to give. That’s the spectrum. Now, where are we falling with that with PCOS? What’s going on and How do we need to think about it? First of all, as we become, as you saw, as we become more and more insulin resistant, even before we hit the threshold in our labs that our doctor starts to recognize as insulin resistant, as soon as those labs cross over into the red, that higher amount of insulin that we’re producing, and then that continues, that higher amount of insulin is telling our ovaries to produce excess androgens. So androgens are basically Basically, testosterone is the primary one. There’s a couple of other ones in there. But essentially, when you hear the word androgen, think testosterone, and that’s going to increase your LH. That elevates your LH, your luteinizing hormone.

That’s the hormone that we need to have a spike in in order to have ovulation. When our luteinizing hormone, our LH hormone, is already elevated, our body has a hard time recognizing a surge. Essentially, Essentially, if you’re already yelling and then you yell a little harder, it’s going to be a lot harder to get someone’s attention. The reason we usually yell, Watch out, is because we’re trying to get someone’s attention. Now, if we’re already talking at an elevated volume, and then we try to elevate it a little bit farther, we don’t have the shock and awe value. Now, in order to have ovulation, we need that shock and awe. If our LH is already elevated, we’re not going to have the shock and awe, and It’s not going to register to our body that we need to finish maturing and release that mature egg into ovulation. When we don’t ovulate, we don’t have the hormone change from one part of the cycle to the second part of the cycle. Every month that we don’t ovulate, it actually lowers our progesterone. There’s other things that also lower our progesterone. But the repeated lack of cycling, the repeated lack of ovulation in and of itself starts to dampen our cycle rhythm.

When we have this elevated LH, it creates a very big problem for our cycle and for our fertility. It takes a while to repair that as well. The other areas that testosterone can affect are facial hair, body hair. We start to get that male pattern of PCOS that we see where we’ll have male pattern hair loss on the head. We may start to grow a mustache. We may have some facial hair, some hair on the neck. We may have some body hair on the chest or on the toes. These are all things that we start, or even just more leg hair than somebody else would have that didn’t have high testosterone. We may have more tendency towards acne, especially if we also have an inflammatory component that’s out of control. These are all things that we’re going to start seeing with testosterone. It also then, because of the cycle changes, the hormones that are related to the cycle, it can start to increase PMS and anxiety and lack of sleep or sleep disturbances and increase stress It starts to throw off some of those more delicate, higher in the pyramid hormones. Back to insulin. I want to move further back towards the healthy side of the spectrum and talk about what’s happening even before you approach the insulin resistance standpoint.

Insulin circulating your system for any reason, especially if it’s doing it in large amounts and in high frequency, it’s going to stimulate those ovaries. This is the part where a lot of people think, Oh, I don’t show up as a problem on labs yet. I’m fine. That’s not my problem. Well, just because your body is compensating for it, just because your cells haven’t gotten sick of the insulin knocking on its door yet, doesn’t mean that the insulin circulating your system isn’t still having an effect. If you’re living on the, I’m not going to eat too many calories, but I’m going to eat the calories that I eat in Skittles and a Coke, and basically live off of little sugar punches to get me through the day with little bursts of energy, you’re constantly spiking your insulin. When we do that, we’re constantly keeping insulin circulating our system. Or maybe It’s just that we eat three high glycemic index foods for meals, high glycemic meals three times a day with two snacks in between. Every two hours, we are spiking our blood sugar. We’re releasing a large amount of insulin. Throughout the day, we’re releasing, we’re releasing, we’re releasing, we’re releasing insulin.

Insulin is constantly circulating our system. Yes, maybe our cells are doing fine with that. Our fasting blood sugar is fine. Our insulin levels are fine. Our hemoglobin A1c, the measure of our blood sugar over a three-month average, it looks fine. However, that’s because our insulin system is compensating, but it’s still constantly releasing insulin. Our ovaries are still constantly constantly being exposed to insulin. In PCOS, our ovaries are very sensitive to that insulin, and they release the excess androgens. If we’re eating a diet that’s constantly stimulating our insulin release, we’re constantly stimulating our ovaries to release those excess androgens, even though our insulin system is still on the healthy end of the spectrum. Hopefully, this starts to shed some light on why insulin becomes a problem with PCOS long before our labs indicate that we have a problem in our insulin and blood sugar system. This is why I use the term the insulin effect in the root cause, because it starts way before insulin resistance has become a problem. It starts way before our body has begun to shut down. Just having the high repeated release of insulin is part of the problem for our PCOS symptoms.

And yes, that high constant release of blood sugar and insulin leading to insulin resistance. It’s the cause of why we’re going to get insulin resistance later. But even before we develop that resistance, just having it present, circulating our system on a continual basis is stimulating our ovaries to release the extra testosterone that’s messing with our cycle and that is messing with our other symptoms that we’re frustrated with with PCOS. Hopefully, that helps to shed some light what’s going on with the insulin root cause for PCOS and why I call it the insulin effect. Also, we talked a little bit about this in the last episode, cortisol, the stress hormone, so perceived stress, stress in the body, stress in your environment, that cortisol also increases the release of insulin. If you have these two things going on, so you have the insulin effect due to more of the foods that you’re eating, maybe due to your current body weight and other lifestyle factors, you’ve got the insulin effect going on. If you additionally have the stress response going on, maybe that’s your secondary PCOS root cause, you’re getting this double whammy and you’re getting a lot of insulin in your system, and it’s really working against you.

So understanding how big of a player insulin is when it comes to polycystic ovarian syndrome is really, really, really important. And I think that a lot of times when we get lab work done and our labs look fine, it starts to get downplayed and set aside. Then we start wondering, why is nothing working? The reason nothing’s working is oftentimes when insulin is circulating in such excess, everything is working against us. So all of our amazing efforts in one area where we thought we had a problem or what we’re trying to do to make ourselves healthy or we’re trying to lose weight, or we’re trying to reduce our inflammation or manage our stress, but we’re just frustrated by the fact that nothing’s working. The reason is it’s because our body is working against us. So hopefully that sheds some light. I know there’s probably going to be questions about this.

So if you have questions about this episode, you know where to find me. I’m over on Instagram @nourishedtohealthy. I would love to continue the conversation with you over there and next week, make sure you hit the subscribe button because next week we’re going to be diving into our next root cause in this little mini-series about root causes and we’ll be talking more about insulin as we work our way up the pyramid and then also how the cortisol, insulin, and inflammation all work together. So be sure not to miss that one next week and until then, bye for now.

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About Show

Welcome to The PCOS Repair Podcast!

I’m Ashlene Korcek, and each week I’ll be sharing the latest findings on PCOS and how to make practical health changes to your lifestyle to repair your PCOS at the root cause.

If you’re struggling with PCOS, know that you’re not alone. In fact, it’s estimated that one in ten women have PCOS. But the good news is that there is a lot we can do to manage our symptoms and live healthy, happy lives.

So whether you’re looking for tips on nutrition, exercise, supplements, or mental health, you’ll find it all here on The PCOS Repair Podcast. Ready to get started? Hit subscribe now

Episode #117: ​​The Stress Response Root Cause

Episode #117: ​​The Stress Response Root Cause

Episode #117: ​​The Stress Response Root Cause

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The Stress Response Root Cause

What you’ll learn in this episode

In this episode, we continue our mini-series about PCOS root causes, about the stress response as a root cause of PCOS. This episode will be peeling back the layers to uncover how our body’s stress mechanisms influence PCOS symptoms. 

Understanding the Stress Response in PCOS

The often overlooked stress response PCOS root cause plays a pivotal role in the exacerbation of PCOS symptoms. This episode will delve into how chronic stress, whether perceived or real, triggers a cascade of hormonal reactions that can lead to or worsen PCOS symptoms.

Cortisol and PCOS

You will learn how this primary stress hormone, when chronically elevated, can lead to increased androgen production, disrupting hormonal balance and contributing to common PCOS symptoms like irregular periods, hair loss, and acne. You will also learn about the interaction between cortisol and insulin and how stress can indirectly cause insulin levels to rise, further exacerbating PCOS symptoms by increasing androgen production.

Practical Insights and Lifestyle Considerations

As we unravel the intricacies of the stress response and its impact on PCOS, we also explore practical steps and lifestyle modifications to mitigate these effects with strategies to reduce stress in daily life, which can have a direct positive impact on managing PCOS symptoms. Plus insights on how to adjust diet and exercise routines to support hormonal balance and reduce the stress response in the body.

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

Let’s Continue The Conversation

Do you have questions about this episode or other questions about PCOS? I would love to connect and chat on a more personal level over on Instagram. My DMs are my favorite place to chat more.

 

So go visit me on IG @nourishedtohealthy.com

 

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Read The Full Episode Transcript Here

Welcome back to the PCOS Repair podcast, where in today’s episode, we are going to dive into our first PCOS root cause of our mini-series on what is going on in the root causes and how are they connected to the symptoms of PCOS. We’ll get into all of this. But symptoms of PCOS are really just the tip of the iceberg of what’s happening deeper in our metabolic and endocrine health. Without further ado, let’s dive into today’s root cause of the stress response.

You’re listening to the PCOS Repair podcast where we explore the ins and outs of PCOS and how to repair the imbalances in your hormones naturally with a little medical help sprinkled in. Hi, I’m Ashlene Korcek, and with many years of medical and personal experience with polycystic ovarian syndrome, it is my joy to watch women reverse their PCOS as they learn to nourish their body in a whole new way. With the power of our beliefs, our mindset, and our environment, and the understanding of our genetics, we can heal at the root cause.

Welcome back to the PCOS Repair podcast where we are diving into the stress response. And before we fully get into cortisol and all things in the hormonal realm of the stress response root cause, I I want to just back up a second and review a little bit of what we talked about last week. We’re currently starting a mini-series here diving into the hormones and their root causes and what’s causing that dysfunction, and then how is that connected to the external symptoms that we experience with PCOS. This way you can understand a little more of how all of the root causes are interconnected and how they’re different. If you missed last week’s episode or it’s been a little while since you’ve listened to it, I recommend you jump back and start there because all of these episodes are very, very connected and build off of each other. Also, I want to remind you that my terminology of how I explain what’s going on in the hormonal metabolic endocrine chemical sphere of our bodies is my unique way of explaining it.

When I say something like a stress response, we get what that means. That’s not a medical term, your doctor is not going to be like, oh, you have stress response PCOS they’re going to say, you have PCOS, you’re experiencing these symptoms. Would you like to try birth control? or metformin has been helpful with PCOS. They’re going to continue talking about PCOS like that. We’re going beyond that to start to explain what is going on in our lifestyle that is affecting what’s going on inside of our body, and then how that’s coming back around to worsen or repair our PCOS hormones. That’s not something that you’re going to hear your doctor talk about. The terminology I’m using is completely my own way of talking about it. It may mimic other people that you hear talking about it, but these are just my best ways of trying to explain it to women on a more practical, less research, technical, medical jargon type of way. All of what we’re talking about is based in pathophysiology, so it’s all based in science. It’s all based in research. The things that I tell you are a combination of well-researched things, although nothing in PCOS is that well-researched, unfortunately, as well as what I have seen in my own experience, as well as my own experience working with hundreds of women and speaking with hundreds of women and other experts in the field of fertility and women’s health and health and fitness, and putting all of that together to try to help explain to you what is going on in our root causes. What I’m really trying to say there is, don’t get hung up on the terminology that I’m using. Use it to help you better understand it but if you go and Google it, you’re going to go down a whole different route because it’s unique to me.

Last week, we talked about the root causes. As a quick recap, these include the base of the pyramid. Basically, think of the pyramid again. If you haven’t listened, again, go back and listen because we talked about the pyramid, at the base of the pyramid, we have cortisol, that’s your stress hormone. That’s the one we’re going to be talking about primarily today. As you move up the pyramid, then we move into insulin. Then as we move up further, we move into inflammation. Then as we move up further, we have a disarray of hormone dysregulation, as well as maybe some nutritional deficiencies. This may have been brought about by other diseases. It’s more superficial. This is where we’re getting into maybe a little bit more superficial lifestyle things. If we have the basis fixed, like we’ve fixed our cortisol or more or less brought our cortisol into balance, our insulin into balance, and our inflammation is subdued, then if we’re still seeing some symptoms, we’re dealing with some of the aftermath chaos, basically, if you will.

Those are the more superficial things, and then that leads straight into those hormones are affecting and leading to our symptoms but essentially, going up that pyramid, each thing from the bottom affects the next thing up and so forth. Cortisol can very much, as you’ll see today, affect insulin. Insulin does not affect cortisol as much. If we have high insulin, it doesn’t necessarily signal the release of cortisol, whereas if we have high cortisol, it will signal the release of insulin. Again, go back and listen so you can review about last week. But for right now, what we’re going to get into is the stress response root cause. Where I want to start with this is what do I mean by stress response?

We all experience and perceive stress differently in our life. Some people find being late very stressful. Some people, my husband, I’ve watched him, it’s like he’s completely and totally unfazed by the fact that he’s late, although he’s driving fast and he’s still rushing and he’s still more on edge but if you checked in with how is he feeling, he is not anxious, stressed about being late. He is, however, going through the motions of, I need to get there quickly. But he sees it almost as more exciting, whereas I see it more as, I really need to get my act together. I’m such a mess. I feel more stressed, more visibly stressed. I use this example because how we perceive stress, how we think about stress, how we take a stressful situation or a high velocity situation or a highly charged situation, and how we deal with it, how we think about it, how we feel about it, what physical reactions, do we start getting sweaty, do we start having our heart rate? And then also what emotional reaction do we have? Do we start beating ourselves up about it? Do we start feeling fear or anxiety, those things? How we react to a situation is so unique person to person and so it’s important as we begin this conversation about their stress response to point out that how our body is perceiving these reactions is actually quite similar. So someone who is like my husband, who is almost thriving on this, I feel more alive. This is exciting. I have to get there quickly and almost heightened awareness versus someone who is almost falling into a puddle of despair over, I’m late now I don’t know what to do, and I’m losing my mind. There’s different responses to the same situation. Both of these are creating a fight or flight response in our body. They are creating an adrenaline release. They’re creating a cortisol release. Essentially, at the primal level, no matter how we’re handling the situation on the surface, no matter if we look like we are completely cool as a cucumber, whether we are flying off the handle, whether we are energized, whether we are drained, however we are showing up in this stressful situation, at a primal level, our body is seeing it as a threat.

At a primal level, when our body sees something as a threat, we go into a fight or flight response. This helps us to be more cognitively clear. This helps us to either hide or to survive. Maybe it’s shutting down hunger so that we can survive if we’re under attack, so we’re not going low blood sugar all of a sudden. It literally affects all of these systems in our body in response to a stimulus and how we respond to that stimulus is actually less relevant than how our primal self is responding to that stimulus.

When our primal response is to release cortisol or to have that fight-and-flight response, that’s where we start to see problems. Now, we want that response there. That’s a really important vital response. It’s a safety mechanism. It’s also what gives us energy throughout the day. Just simply waking up in the morning, we get this nice, lovely surge of cortisol, or we should. Then it tapers off to allow us to slow down and relax at the end of our day. This is normal. It’s a good thing. Also, if there’s an emergency, we want to have that adrenaline reserve where we can have that fight flight response. Where we get ourselves into trouble is when we live in that, and it becomes a chronic state of being. Maybe one minute it’s because we’re running late. Maybe it’s another minute because of an interpersonal relationship. Maybe another minute It’s because we’re overthinking something, or maybe it’s because we’re building up anxiety over going into our second year of infertility, and it’s going to happen for me, or maybe it’s from some grief and sadness over disappointments or some tragedy in your life. But whatever it is that is causing this constant amount, and we live in a very fast-paced society, it’s very easy to become comfortable with this high stress living.

When we don’t care for our high stress living, our primal self goes into a constant state, maybe not the highest state of fight and Maybe you can rev it up a little bit from time to time, but it’s living in a heightened state more times than not. When we’re living in that, that’s when we start to develop this stress response, constantly high cortisol, and at some point, we may even drain our cortisol and go into almost a cortisol crash, or we’ve used it all up and our body is no longer responding. It’s like we’ve responded so much, we’ve called wolf almost so much, or we’ve exhausted our cortisol system to where it’s not giving enough, and then we really feel the fatigue. Then it’s important to note that not only those big stressors, the emotional stressors, the busyness and deadline stressors, the running late, or the overwhelming stressors, interpersonal, family, life, all those stressors. Besides those, there are a different category of things that our body at a primal level perceives as stress.

Those include calorie deficits. If you are someone who has a history of crash dieting or extreme dieting, where you really cut those calories more than about 1-200 calories per day in deficit, and you did that for periods of time to drop weight quickly and then regained that weight when you stopped living in a calorie deficit or yo-yo dieting, sometimes it’s called. If you have a history of doing that, your body has been living in states of extreme stress because to our body, it doesn’t understand that I’m choosing not to feed you. What it understands at a primal level is we must be in a time of famine and starvation and we may die. From that standpoint, our body goes into a very fearful response and goes into conservation mode and shuts down the metabolism and does all of these things that it doesn’t come back out of the diet and then trust that everything’s fine and that’s not going to happen again. Especially when we do it repeatedly. We train our body be fearful of starvation. Our body doesn’t look at it the same way as we do where it’s like, Oh, there’s plenty over here on this leg, and there’s plenty right here on my tummy. We don’t need to worry about starving. It looks at it like, I’m not getting fed today, therefore, we don’t know when our next meal is coming from, and it goes into a severe stress response.

Another stress response that we don’t always perceive as stress, in fact, it actually has a stress release, and that exercise. This is an area where I actually disagree with most people, most experts, when it comes to this topic on PCOS and for a lot of reasons. But there is research that points to when you’re exercising, you get a rise in cortisol. The longer and more intense and more endurance, so long distance or long time frame, intense workouts, the more that bump in cortisol. Now, I would argue that for the most part and for most people, this bump in cortisol is fairly negligible and the benefits far away the downsides because that small bump in cortisol is accompanied by many, many, many other hormones that are extremely valuable. So all of the endorphins, all the serotonin, all of the feel-good hormones that come from exercise, all of the calming hormones that come from exercise are really good. This is where, though, for someone who’s dealing with stress response, PCOS, there are some significant exercise considerations but I also think that this one area where you could work against yourself a little bit with the stress response, I think that one, if you’re doing all the other things right, this would work against you mildly. Then two, it’s a very easy one to put into check, and all of the benefits are so important that I wouldn’t say stop it altogether. I wouldn’t say just go to yoga and low-intensity workouts. I think that the intense workouts, they create an entirely different benefit, and they shouldn’t be overlooked entirely.

Also, This is a small sector of PCOS women. It is oftentimes an adjoining root cause, which we’ll talk about as we go, but it’s not high percentage of stress response being the primary and only root cause of PCOS for most women. To tell women that exercise may be harmful for PCOS or that intense or certain types of exercise may be harmful for PCOS is such a disservice because when we deal with things like insulin or inflammation, exercise comes into such a huge play. It actually does with stress response, too, when we see how to repair those root cause hormones. When it comes to exercise, it’s important to be aware that this can be perceived as a stressor on the body, but it also it’s more of a, we need to understand it. We need to understand what we’re doing. It becomes very individual. How are you feeling after your workout? Are you increasing gradually? Are you going out and just being a weekend warrior? There’s different ways that we can address our PCOS exercise that allows for really, really, really beneficial workouts without the detrimental results.

Those are some things that can cause stress. Now, what is going on, and this is the important part I want you to understand in the point of this particular episode is what is going on When we raise our cortisol, what is happening in the body and how is this affecting PCOS? Cortisol and stress affects us in two ways. One, when we’re experiencing stress, and again, we’re talking about stress at that primal level. However you think about stress and however you feel stress in your life, we’re going deeper than that to how is your body perceiving at a very primal, primitive level.

Then another that we can have androgen excess is that the stress hormone. So one, the stress tells our adrenals to release extra androgens. It can also tell our body to release more cortisol. So now we have excess androgens and excess cortisol going through our bloodstream. That extra cortisol on a chronic level is going to tell our body to release more insulin. The reason it releases more insulin is it wants to get that blood sugar, any blood sugar it can, into our cells because we need that heightened fight and flight response. It raises our insulin.

That excess insulin tells our ovaries to release more androgens. Now we have even more androgens into our system and flowing around through our blood. That’s telling our LH. It raises our LH, which messes with our FSH, which messes with our ovulation, which messes with our progesterone, which messes with our periods, which messes with our fertility, which also, again, mess with the other PCOS symptoms of acne, of hair loss, of hair growth on the face, hair loss on the head. Then having insulin present in the system. Now, again, insulin is a good hormone that has its time and place but when it’s just circulating around aimlessly, you know what it tells our body to do? It says, store fat, don’t burn it. If you’re trying to lose a little bit of weight and you have excess insulin constantly circulating your system, you’re fighting yourself. On one hand, you’re in a calorie deficit saying, lose weight. Your calorie deficit, if it’s too aggressive, is increasing your cortisol because your body’s stressed. Then that increase of cortisol is raising your insulin, the insulin saying, don’t lose weight. This is a very vicious cycle. To calm all of this down, it’s really important to understand how that stress response is going, what could our body be perceiving as stress, and to dive into that type of root cause.

Again, as we wrap up today, I want to remind you that these root causes, everyone has every single one of them that has PCOS. Actually, probably in humans in general, but in PCOS, we are more sensitive to these. We tend to have them show up at a younger age, and our body is actually just more sensitive to both the root causes and the environmental stimuli that triggers these root causes. We’re just a little bit more sensitive to all of it, so we see it show up bigger, stronger but we all have all of these. We all have the tendency towards inflammation if we don’t care for our health. We all have the stress response. If we’re not being mindful of it, we all have the insulin effect, whether or not it’s as strong or as early on in life as other people. Even though ours in PCOS tends to show up earlier, everyone at some point, if they eat certain ways and have certain lifestyle factors, will eventually head towards a prediabetic or diabetic health situation as well, but when we’re seeing what is going on in, say, our root cause, what we’re looking for is what is that primary root cause? What is the one that’s the leading one for us? And so a lot of times we’ll see stress response as a close secondary response to both inflammation and the insulin effect and so you may find that you have these combo ones. Combo ones are completely normal. Essentially, we would just look at what is your primary root cause, focus on the low-hanging fruit of that one. We’ll also incorporating what would be also beneficial for that secondary root cause. These are oftentimes very linked. You see the insulin connection very easily there. There’s a lot of things that overlap and we can start to address in tandem, making our efforts more focused and effective.

I hope that overview of what is even going on in these root causes, because I know I talk about them all the time, and I’ve been getting a lot of questions about, Well, what’s going on? Why is this happening the way it’s happening? I think I have multiple root causes. Well, yes, you might. You may have one that’s prominent. You may have ones that are all fairly lowly. They’re there, but they’re all there. We see different combinations of all of that. It’s just learning how to read what’s going on in our body so that we can care for it, nurture it, and ultimately repair that root cause imbalance and pair our PCOS.

With that, if you have any follow-up questions on this, feel free to find me over at Instagram. My handle is @Nourishedtohealthy. I love hearing from everybody over there. My DMs have been very full. If you have a question and I somehow miss it, feel free to message me again because sometimes they hide in my hidden messages. I’ve been finding those more easily lately because I know to look for them now but if I’ve missed any of your messages, I apologize. Instagram has a way of sometimes hiding them. I don’t know why. With that, until next time. Bye for now.

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About Show

Welcome to The PCOS Repair Podcast!

I’m Ashlene Korcek, and each week I’ll be sharing the latest findings on PCOS and how to make practical health changes to your lifestyle to repair your PCOS at the root cause.

If you’re struggling with PCOS, know that you’re not alone. In fact, it’s estimated that one in ten women have PCOS. But the good news is that there is a lot we can do to manage our symptoms and live healthy, happy lives.

So whether you’re looking for tips on nutrition, exercise, supplements, or mental health, you’ll find it all here on The PCOS Repair Podcast. Ready to get started? Hit subscribe now